Find BENADRYL® dosage information for adults, children, and toddlers and learn how much you and your family should take with our allergy medicine product-dosing guide. Detailed Diphenhydramine dosage information for adults and children. Includes dosages for Insomnia, Allergic Rhinitis, Allergic Reaction and more; plus renal, liver and dialysis adjustments. Dosage Forms: Oral, IM, IV Common Trade Names: Benadryl Adult Dosing Allergic reaction Oral: 25-50mg q4-8h, max 300mg/day IM/IV: 10-50mg/dose Parkinsonian symptoms Oral: 25-50mg tid-QID IM/IV: 10-50mg/dose Insomnia: 50mg PO qhs Injectable 1% diphenhydramine (10 mg/mL) can be used as a local anesthestic alternative to ester/amide anesthetics [1] Medscape - Hypersensitivity reactions, insomnia, antihistamine-specific dosing for Benadryl, Nytol (diphenhydramine), frequency-based adverse effects, comprehensive interactions. They are 2x the strength of Benadryl Ultra-tabs, making them ideal for those who need a little extra help when it comes to alleviating their symptoms. They are easy to take. The recommended adult Benadryl dosage for allergies is 1 to 2 tablets or capsules by mouth every 4 to 6 hours as needed. You shouldn’t take more than 6 doses (300 mg) in a 24-hour period. Official answer: The maximum safe Benadryl (diphenhydramine) dose for adults is 50 to 100 mg for a single dose with a daily maximum of. Find the recommended amount of Benadryl to give your child based on age and weight using the St. Louis Children's Hospital Benadryl dosage chart. Calculate the appropriate diphenhydramine (Benadryl®) dose based on body weight, age, and formulation. This tool supports liquid, chewable, tablet, and capsule forms for both children and adults. For adults with common cold symptoms, the typical dosage of Benadryl is 25 to 50 mg (one to two tablets) taken every 4 to 6 hours, or as directed by your doctor.